Review Articles

Donald H Lee 1, Kaitlyn Reasoner 2, Sasidhar Uppuganti 1, Mihir J Desai 1, Jeffry S Nyman 1PMID: 35778010DOI: 10.1063/5.0082751 Impact microindentation is a new technique that measures the resistance of a patient’s bone to micro-indentation but has not yet been implemented in an intraoperative setting. To assess the technique’s safety and utility, we acquired microindentation measurements of bone material strength index (BMSi) using the …

Intraoperative use of impact microindentation to assess distal radius bone quality Read More »

Manuela Schoeb 1, Neveen A T Hamdy 1, Frank Malgo 1, Elizabeth M Winter 1, Natasha M Appelman-Dijkstra 1 Front Endocrinol (Lausanne). 2020 Feb 7;11:15. doi: 10.3389/fendo.2020.00015. eCollection 2020. PMID: 32117052 PMCID: PMC7020781 DOI: 10.3389/fendo.2020.00015 The current gold standard for the diagnosis of osteoporosis and the prediction of fracture risk is the measurement of bone mineral density (BMD) using dual energy x-ray absorptiometry (DXA). A low BMD is clearly associated …

Added Value of Impact Microindentation in the Evaluation of Bone Fragility: A Systematic Review of the Literature Read More »

John P. Bilezikian (Editor-in-Chief) ISBN: 978-1-119-26656-3 November 2018 Wiley-Blackwell 1136 Pages The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer …

Chapter 36 – Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 9th Edition Read More »

Sabina Herrera 1, Adolfo Diez-Perez 2 Bone. 2017 Feb;95:175-182. DOI: 10.1016/j.bone.2016.11.003. Epub 2016 Nov 11. PMID: 27840302 DOI: 10.1016/j.bone.2016.11.003 Densitometry and imaging techniques are currently used in clinical settings to measure bone quantity and spatial structure. Recently, Reference Point Indentation has opened the possibility of directly assessing the mechanical characteristics of cortical bone in living individuals, adding a new dimension …

Clinical experience with microindentation in vivo in humans Read More »

Andrew Chang 1, Garrett W Easson 1, Simon Y Tang 1 2 3 Clin Rev Bone Miner Metab. 2018 Sep;16(3):87-94. doi: 10.1007/s12018-018-9249-9. Epub 2018 Sep 12. PMID: 30983912 PMCID: PMC6457660 DOI: 10.1007/s12018-018-9249-9 Over the last thirty years, it has become increasingly clear the amount of bone (e.g. ‘bone quantity’) and the quality of the bone matrix (e.g. ‘bone quality’) both critically contribute to bone’s tissue-level mechanical behavior and …

Clinical measurements of bone tissue mechanical behavior using reference point indentation Read More »